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SU 5416 (CAS 204005-46-9)




Product specification

Formula: C15H14N2O
MW: 238.28
Purity: ≥99%
Appearance: Yellow to yellow orange solid
Solubility: Soluble to 100 mM in DMSO and to 100 mM in Ethanol
Storage: -20°C
CAS Number: 204005-46-9
Synonyms: Semaxinib
Cat.number: VD-AM-0057

Product Description

SU 5416 (CAS 204005-46-9) is an inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases c-Kit, MET, FLT3 and RET. Displays no activity against EGFR, HER2, IGF1R and PDGFR. Inhibits tumor vascularization and growth of multiple tumor types. 



Product References
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2. Smolich et al (2001) Blood 97 1413.
3. Mologni et al (2006) J.Mol.Endocrinol. 37 199.