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VD-CAN-0003-0001-5mg 50 USD
VD-CAN-0003-0050-50mg 300 USD

AM 281




Product specification

Formula: C21H19Cl2IN4O2
MW: 555.21
Purity: ≥98%
Appearance: White to off-white powder.
Solubility: Soluble in MeOH (1mg/ml) or DMSO.
Storage: +4°C.
CAS Number: 202463-68-1
Synonyms: 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-
N-morpholino-1H-pyrazole-3-carboxamide
Cat.number: VD-CAN-0003

Product Description

Analog of the cannabinoid receptor (CB) antagonist SR 141716A. Potent and selective CB1 receptor antagonist/inverse agonist (Ki=14nM).



Product References
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2. Gatley, S.J., et al. 1998. J. Neurochem. 70: 417-423.
3. Werner, N.A., et al. 2003. Brain Res. 967: 290-292.
4. Kadoi, Y., et al. 2005. Br. J. Anaesth. 94: 563-568.

5. F Molina-Holgado et al. Neuroprotective effects of the synthetic cannabinoid HU-210 in primary cortical neurons are mediated by phosphatidylinositol 3-kinase/AKT signaling. Mol. Cell. Neurosci. 2005, 28, 189-194.