CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-0156-0005-5mg | $100 | ||
| VD-OEIA-0156-0050-50mg | $900 |
γ–Secretase Inhibitor I
$100.00 – $900.00
Product Specification
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Appearance:
White Solid
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CAS Number:
133407-83-7
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Cat.number:
VD-OEIA-0156
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Formula:
C26H41N3O5
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MW:
475.6
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Purity:
>=95%
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Solubility:
50% Acetic Acid or DMSO
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Storage:
-20°C. Higroscopic.
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Synonyms:
Z-LLNle-CHO; Z-Leu-Leu-Nle-CHO (Nle = Norleucine)
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Size:
50mg, 5mg
Description
Cell permeable. Inhibits γ-secretase, a protease that cleaves the Amyloid Precursor Protein (APP) to generate β-amyloid protein. Inhibition of this enzyme is believed to aid in the prevention of Alzheimer’s disease.
1.Skovronsky, D.M., et al. 2000. Biochemistry 39, 810.
2.Hartmann, T., et al. 1997. Nat. Med. 3, 1016.
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