CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-PI-0181-0001-1mg | $50 | ||
| VD-PI-0181-0005-5mg | $220 |
γ-Secretase Inhibitor II
$50.00 – $220.00
Product Specification
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Appearance:
White Solid
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CAS Number:
N/A
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Cat.number:
VD-PI-0181
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Formula:
C33H57F2N5O9
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MW:
705.8
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Purity:
>=90%
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Solubility:
DMSO
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Storage:
-20°C
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Synonyms:
MW167
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Size:
1mg, 5mg
Description
A cell-permeable, reversible and selective peptidomimetic inhibitor of γ-secretase (IC50 = 13 µM for Aβ). Displays only weak inhibitory activity against calpain II (IC50 = 100 µM in a purified enzyme assay).
1.Wolfe, M.S., et al. 1999. Biochemistry 38, 4720.
2.Wolfe, M.S., et al. 1998. J. Med. Chem. 41, 6.
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