CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-NP-0052-0010-10mg | $148 | ||
| VD-NP-0052-0100-100mg | $1350 |
Ac-DEVD-AFC (CAS 201608-14-2)
$148.00 – $1,350.00
Product Specification
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Appearance:
White powder.
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CAS Number:
201608-14-2
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Cat.number:
VD-NP-0052
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Formula:
C30H34F3N5O13
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MW:
729.61
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Purity:
≥90% (HPLC)
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Solubility:
H2O: soluble1 mg/mL
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Storage:
-20°C
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Synonyms:
N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoromethylcoumarin
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Size:
100mg, 10mg
Description
Ac-DEVD-AFC (CAS 201608-14-2) is a fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase. The 7-amido-4-trifluoromethylcoumarin derivative has better membrane permeability than the 7-amido-4-methylcoumarin derivative.
1. Gurtu, V., et al., Anal. Biochem. 251, 98-102, (1997).
2. Marks, N., et al., J. Neurosci. Res. 52, 334-341, (1998).
3. Martins, L.M., Blood 90, 4283, (1997).
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