Acyclovir (CAS 59277-89-3)

$50.00$475.00

Product Specification

  • Appearance
    :

    White crystalline solid

  • CAS Number
    :

    59277-89-3

  • Formula
    :

    C8H11N5O3

  • Cat.number
    :

    VD-HV-0098

  • MW
    :

    225.21

  • Purity
    :

    >=99% by (HPLC)

  • Solubility
    :

    50 mM in 1eq. HCl and to 20 mM in DMSO

  • Storage
    :

    RT

  • Synonyms
    :

    Acycloguanosine, NSC 645011

  • Size
    :

    500mg, 50mg

SKU: VD-HV-0098 Categories: ,

Product Variations

Product # Price Quantity  
VD-HV-0098-0050-50mg $50
VD-HV-0098-0500-500mg $475

Description

Acyclovir (CAS 59277-89-3) is an antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC50 values are 0.85 and 0.86 μM respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy).

1. Elion et al (1977) Proc.Natl.Acad.Sci.USA. 74 5716.
2. Hayashi et al (2006) J.Gene.Med. 8 1056.
3. Suzuki et al (2006) Antiviral Res. 72 157.

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