Antipain

$220.00$900.00

Product Specification

  • Appearance
    :

    Yellow powder

  • CAS Number
    :

    37691-11-5

  • Cat.number
    :

    VD-Ant-0334

  • Formula
    :

    C27H44N10O6

  • MW
    :

    604.71

  • Purity
    :

    ≥95%

  • Storage
    :

    Longterm storage temperature: -20 ± 5 °C

  • Synonyms
    :

    Chemical name: [(S)-1-Carboxy-2-phenyl-ethyl]- carbamoyl-Arg-Val-Arg-aldehyde

  • Size
    :

    250mg, 50mg

SKU: VD-Ant-0334 Category:

Product Variations

Product # Price Quantity  
VD-Ant-0334-0050-50mg $220
VD-Ant-0334-0250-250mg $900

Description

A reversible inhibitor of Ser and Cys proteases with an activity spectrum comparable to leupeptin (N-1000). H-1765 inhibited transformation of NIH3T3 cells after transfection with an activated H-ras oncogene (Cox et al.). Vaccari et al. used antipain for evaluating the role of proteases in the process of malignant transformation of BALB/c 3T3 cells.

H.Ikezawa et al., J. Antibiot., 25, 738 (1972).
H.Suda et al., J. Antibiot., 25, 263 (1972).
S.Umezawa et al., J. Antibiot., 25, 267 (1972).
L.R.Cox et al., Cancer Res., 51, 4810 (1991).
M.Vaccari et al., Anticancer Res., 19, 589 (1999).

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