CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-0058-0010-10mg | $100 | ||
| VD-OEIA-0058-0050-50mg | $450 |
AY 9944 dihydrochloride
$100.00 – $450.00
Product Specification
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Appearance:
White Solid
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CAS Number:
366-93-8
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Cat.number:
VD-OEIA-0058
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Formula:
C22H28Cl2N2.2HCl
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MW:
464.30
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Purity:
>=99%.
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Solubility:
Soluble to 50 mM in Water.
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Storage:
Desiccate at RT
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Synonyms:
N/A
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Size:
10mg, 50mg
Description
Inhibitor of hedgehog (Hh) signaling, possibly via several mechanisms. Inhibits Δ7-dehydrocholesterol reductase (IC50 = 13 µM), thus reduces cholesterol biosynthesis, and also inhibits cholesterol esterification. May also directly block the cellular response to Hh proteins. Teratogenic in vivo.
1.Kraml et al (1964).Biochem.Biophys.Res.Comm. 15 455.
2.Cooper et al (1998).Science 280 1603.
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