Biphenylindanone A (CAS 866823-73-6)

$120.00$400.00

Product Specification

  • Appearance
    :

    Off-white solid.

  • CAS Number
    :

    866823-73-6

  • Cat.number
    :

    VD-OEIA-1067

  • Formula
    :

    C30H30O4

  • MW
    :

    454.56

  • Purity
    :

    >=98%

  • Solubility
    :

    DMSO to 100 mM.

  • Storage
    :

    RT. Keep cool and dry.

  • Synonyms
    :

    BINA

  • Size
    :

    10mg, 50mg

Product Variations

Product # Price Quantity  
VD-OEIA-1067-0010-10mg $120
VD-OEIA-1067-0050-50mg $400

Description

Biphenylindanone A (CAS 866823-73-6) is a selective positive allosteric modulator of mGlu2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2). Displays no effect on glutamate-induced activation of other mGlu receptor subtypes. Exhibits antipsychotic and anxiolytic properties in mice.

1.Bonnefous et al (2005). Bioorg.Med.Chem.Lett. 15 4354.
2.Galici et al (2006). J.Pharmacol.Exp.Ther. 318 173.

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