Calpain Inhibitor XII

$65.00$275.00

Product Specification

  • Appearance
    :

    Faint yellowish glassy semi-solid.

  • CAS Number
    :

    N/A

  • Cat.number
    :

    VD-PI-0154

  • Formula
    :

    C26H34N4O5

  • MW
    :

    482.6

  • Purity
    :

    >=90%

  • Solubility
    :

    DMSO

  • Storage
    :

    +2°C to +8°C. Protect from light.

  • Synonyms
    :

    Z-Leu-Nva-CONH-CH2-2-Pyridyl

  • Size
    :

    1mg, 5mg

SKU: VD-PI-0154 Categories: ,

Product Variations

Product # Price Quantity  
VD-PI-0154-0001-1mg $65
VD-PI-0154-0005-5mg $275

Description

A cell-permeable dipeptidyl α-ketoamide compound that acts as a potent, selective, reversible, and active site inhibitor of calpain-1 (Ki = 19 nM). Shown to inhibit calpain-2 (Ki = 120 nM) and cathepsin-B(Ki = 750 nM) at higher concentrations.

1.Li, Z., et al. 1996. J. Med. Chem. 39, 4089.

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