CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-0221-0010-10mg | $70 | ||
| VD-OEIA-0221-0050-50mg | $300 |
Casein Kinase II Inhibitor VI, TMCB (CAS 905105-89-7)
$70.00 – $300.00
Product Specification
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Appearance:
White powder.
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CAS Number:
905105-89-7
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Cat.number:
VD-OEIA-0221
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Formula:
C11H9Br4N3O2
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MW:
534.8
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Purity:
>=97% by HPLC.
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Solubility:
DMSO to 25 mM.
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Storage:
-20°C.Stock solutions are stable for up to 3 months at -20°C.
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Synonyms:
ERK8 Inhibitor I; K66; Erk Inhibitor VI
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Size:
10mg, 50mg
Description
A cell-permeable tertabromobenzimidazolo TBB analog that acts as a highly selective (IC50 >10 µM against 71 other kinases) ATP-competitive inhibitor against CK2 (IC50 = 500 nM; Ki = 250 nM) and ERK8 (IC50 = 500 nM). K66 is reported to be more selective than either TBB or DMAT and selective CK2 inhibition by K66 is shown to be cytotoxic to non-ERK8-expressing Jurkat cells.
1.Pagano, M.A., et al. 2008. Biochem. J. 415, 353.
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