Product Variations
Product # | Price | Quantity | |
---|---|---|---|
VD-ESA-0017-0010-10mg | $110 | ||
VD-ESA-0017-0050-50mg | $400 |
$110.00 – $400.00
White crystalline solid
1215548-30-3
VD-ESA-0017
C23H28N4O3.HCl
444.95
>99%
100 mM in water and to 100 mM in DMSO.
+4˚C
CFM 1571 hydrochloride
10mg, 50mg
Product # | Price | Quantity | |
---|---|---|---|
VD-ESA-0017-0010-10mg | $110 | ||
VD-ESA-0017-0050-50mg | $400 |
CFM 1571 hydrochloride (CAS 1215548-30-3) is a soluble guanylyl cyclase (sGC) activator (EC50 = 5.49 μM). Does not activate adenylyl cyclase, shows no significant inhibition of phosphodiesterases and displays minimal inhibition of iNOS (25%) and nNOS (17%). Inhibits collagen-stimulated platelet aggregation in vitro (IC50 = 2.84 μM).
1. Selwood et al (2001) J.Med.Chem. 44 78.
2. Evgenov et al (2006) l. Nat.Rev.Drug Discov. 5 755.
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