CFM 1571 hydrochloride (CAS 1215548-30-3)

$110.00$400.00

Product Specification

  • Appearance
    :

    White crystalline solid

  • CAS Number
    :

    1215548-30-3

  • Cat.number
    :

    VD-ESA-0017

  • Formula
    :

    C23H28N4O3.HCl

  • MW
    :

    444.95

  • Purity
    :

    >99%

  • Solubility
    :

    100 mM in water and to 100 mM in DMSO.

  • Storage
    :

    +4˚C

  • Synonyms
    :

    CFM 1571 hydrochloride

  • Size
    :

    10mg, 50mg

SKU: VD-ESA-0017 Category:

Product Variations

Product # Price Quantity  
VD-ESA-0017-0010-10mg $110
VD-ESA-0017-0050-50mg $400

Description

CFM 1571 hydrochloride (CAS 1215548-30-3) is a soluble guanylyl cyclase (sGC) activator (EC50 = 5.49 μM). Does not activate adenylyl cyclase, shows no significant inhibition of phosphodiesterases and displays minimal inhibition of iNOS (25%) and nNOS (17%). Inhibits collagen-stimulated platelet aggregation in vitro (IC50 = 2.84 μM).

1. Selwood et al (2001)  J.Med.Chem. 44 78.
2. Evgenov et al (2006) l. Nat.Rev.Drug Discov. 5 755.

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