CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-1032-0005-5mg | $150 | ||
| VD-OEIA-1032-0025-25mg | $550 |
cPEPCK inhibitor
$150.00 – $550.00
Product Specification
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Appearance:
N/A
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CAS Number:
628279-07-2
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Cat.number:
VD-OEIA-1032
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Formula:
C25H26FN5O3
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MW:
463.52
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Purity:
>98 %
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Solubility:
N/A
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Storage:
N/A
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Synonyms:
N-{4-[3-Butyl-1-(2-fluoro-benzyl)-2,6-dioxo-2,3,6,9- tetrahydro-1H-purin-8-ylmethyl]-phenyl}-acetamide
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Size:
25mg, 5mg
Description
The first GTP-competitive inhibitor of human cytosolic phosphoenolpyruvate carboxykinase (PEPCK or cPEPCK) with low submicormolar IC50 values.
1. LH Foley et al. Modified 3-alkyl-1,8-dibenzylxanthines as GTP-competitive inhibitors of phosphoenolpyruvate carboxykinase. Bioorg Med Chem Lett. 2003, 13(20), 3607-10.
2. LH Foley et al. X-ray structures of two xanthine inhibitors bound to PEPCK and N-3 modifications of substituted 1,8-dibenzylxanthines. Bioorg Med Chem Lett. 2003, 13(21), 3871-4.
3. SL Pietranico et al. C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase. Bioorg Med Chem Lett. 2007, 17(14), 3835-9.
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