CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-Ant-0255-0001-1g | $40 | ||
| VD-Ant-0255-0005-5g | $170 |
Cycloheximide
$40.00 – $170.00
Product Specification
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Appearance:
Off-white solid
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CAS Number:
66-81-9
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Cat.number:
VD-Ant-0255
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Formula:
C15H23NO4
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MW:
281.35
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Purity:
≥93.0% (HPLC)
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Solubility:
EtOH or MeOH
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Storage:
+15°C to +30°C .
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Synonyms:
Actidione, Naramycin A
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Size:
1g, 5g
Description
Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.
Inhibits protein biosynthesis in eukaryotic cells by binding with the 80S ribosome1.
Christner, C., et al. 1999. J. Med. Chem. 42, 3615. Lu, Q. and Mellgreen,R.L. 1996. Arch. Biochem. Biophys. 334, 175. Chow, S.C., et al. 1995. Exp. Cell Res. 216, 149. Waring, P. 1990. J. Biol. Chem. 265, 14476. Obrig, T.G., et al. 1971. J. Biol. Chem. 246, 174. Pestka, S. 1971. Annu. Rev. Microbiol. 25, 487.
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