Cytoplasmic Dynein Inhibitor, Ciliobrevin D

$150.00$400.00

Product Specification

  • Appearance
    :

    Orange powder.

  • CAS Number
    :

    N/A

  • Cat.number
    :

    VD-OEIA-0216

  • Formula
    :

    C₁₇H₈Cl₃N₃O₂

  • MW
    :

    392.6

  • Purity
    :

    >=99%.

  • Solubility
    :

    DMSO.

  • Storage
    :

    -20°C.

  • Synonyms
    :

    AAA+ ATPase motor cytoplasmic dynein inhibitor

  • Size
    :

    100mg, 25mg

Product Variations

Product # Price Quantity  
VD-OEIA-0216-0025-25mg $150
VD-OEIA-0216-0100-100mg $400

Description

Cytoplasmic Dynein Inhibitor (Ciliobrevin D) is a cell-permeable benzoyl dihydroquinazolinone derivative that acts as a reversible and specific blocker of AAA+ ATPase motor cytoplasmic dynein and disrupts spindle pole focusing, cold-stable microtubule formation, kinetochore-microtubule attachment, and melanosome aggregation in a dose-dependent manner.
1.Firestone, A., et al. 2012. Nature. 484, 125.

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