DNA-PK Inhibitor (CAS 20357-25-9)

$120.00$350.00

Product Specification

  • Appearance
    :

    Bright yellow solid.

  • CAS Number
    :

    20357-25-9

  • Cat.number
    :

    VD-DDR-2001

  • Formula
    :

    C₉H₉NO₅

  • MW
    :

    211.2

  • Purity
    :

    ≥90% by GC.

  • Solubility
    :

    DMSO

  • Storage
    :

    +2°C to +8°C.

  • Synonyms
    :

    DMNB; 4,5-Dimethoxy-2-nitrobenzaldehyde

  • Size
    :

    100mg, 25mg

SKU: VD-DDR-2001 Category:

Product Variations

Product # Price Quantity  
VD-DDR-2001-0025-25mg $120
VD-DDR-2001-0100-100mg $350

Description

DNA-PK Inhibitor (CAS 20357-25-9) is a cell-permeable vanillin derivative that acts as a potent and selective inhibitor of DNA-PK (DNA-dependent protein kinase) activity (IC50 = 15 µM) and DNA-PK-mediated DSB (double strand break) DNA repair by NHEJ (non-homologous DNA-end-joining).

1.Willmore, E., et al. 2004. Blood,103, 4659.
2.Durant, S., and Karran, P. 2003. Nucleic Acids Res. 31, 5501.

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