CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-IS-0101-0010-10mg | $80 | ||
| VD-IS-0101-0050-50mg | $350 |
Fasudil hydrochloride (CAS 103745-39-7)
$80.00 – $350.00
Product Specification
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Appearance:
White to off-white solid.
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CAS Number:
103745-39-7
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Cat.number:
VD-IS-0101
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Formula:
C14H17N3O2S.HCl
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MW:
327.83
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Purity:
≥98% (HPLC)
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Solubility:
Soluble to 100 mM in H2O and to 75 mM in DMSO
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Storage:
RT
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Synonyms:
HA 1077
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Size:
10mg, 50mg
Description
Fasudil hydrochloride (CAS 103745-39-7) is a cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM). Ca2+ antagonist and vasodilator. Also inhibits proliferation of vascular smooth muscle cells.
1. Shirotani et al (1992) J.Pharmacol.Exp.Ther. 259 738.
2. Arai et al (1993) Biochem.Pharmacol. 46 1487.
3. Satoh et al (1996) Br.J.Pharmacol. 118 1592.
4. Sward et al (2000) J.Physiol. 522 33.
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