CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-0219-0010-10mg | $100 | ||
| VD-OEIA-0219-0050-50mg | $400 |
FIPI (CAS 939055-18-2)
$100.00 – $400.00
Product Specification
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Appearance:
Crystalline solid
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CAS Number:
939055-18-2
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Cat.number:
VD-OEIA-0219
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Formula:
C23H24FN5O2
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MW:
421.5
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Purity:
>98%
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Solubility:
~0.25 mg/ml in EtOH, ~20 mg/ml in DMF & DMSO,
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Storage:
-20°C.
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Synonyms:
5-Fluoro-2-Indolyl des- Chlorohalopemide
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Size:
10mg, 50mg
Description
FIPI (CAS 939055-18-2) is a potent phosholipase D (PLD) inhibitor (IC50 values are 20 and 25 nM for PLD2 and PLD1 respectively). Ameliorates PLD2-driven suppression of membrane ruffling and cell spreading. Orally available.
1. Su, W., Yeku, O., Olepu, S., et al. Mol. Pharmacol. 75(3), 437-446 (2009).
2. Monovich, L., Mugrage, B., Quadros, E., et al. Bioorg. Medicinal Chem. Letters 17, 2310-2311 (2007).
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