CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-0033-0001-1mg | $80 | ||
| VD-OEIA-0033-0010-10mg | $550 |
GSK-3 Inhibitor IX
$80.00 – $550.00
Product Specification
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Appearance:
Dark red solid
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CAS Number:
710323-61-8
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Cat.number:
VD-OEIA-0033
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Formula:
C17H12BrN3O2
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MW:
370.2
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Purity:
>=97%
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Solubility:
DMSO
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Storage:
+2°C to +8°C. Protect from light.
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Synonyms:
1-Methyl-BIO; MeBIO
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Size:
10mg, 1mg
Description
A cell-permeable N-methylated analog of GSK-3 Inhibitor IX, BIO that serves as a relevant kinase inactive control (IC50>92 µM for Cdk1/B, > 100 µM for Cdk5/p25, and GSK-3α/β). Acts as a potent ligand for aryl hydrocarbon receptor (AhR; EC50=20 nM and 93 nM for yeast and hepatoma reporter systems, respectively) and displays antiproliferative properties.
1.Knockaert, M., et al. 2004. Oncogene 23, 4400.
2.Polychronopoulos, P., et al. 2004. J. Med. Chem. 47, 935.
3.Meijer, L., et al. 2003. Chem. Biol. 10, 1255.
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