CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-0012-0050-10mg | $110 | ||
| VD-OEIA-0012-0200-50mg | $400 |
HNHA
$110.00 – $400.00
Product Specification
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Appearance:
Crystalline solid.
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CAS Number:
926908-04-5
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Cat.number:
VD-OEIA-0012
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Formula:
C17H21NO2S
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MW:
303.4
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Purity:
≥95%
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Solubility:
DMSO (100 mg/ml), MeOH (10 mg/ml)
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Storage:
+2°C to +8°C. Protect from light.
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Synonyms:
Histone Deacetylase Inhibitor VI
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Size:
10mg, 50mg
Description
A cell-permeable hydroxyamide-based SAHA analog that potently inhibits histone deacetylase (HDAC) activity (IC50=100 nM). Shown to induce histone acetylation and p21 transcription with concomitent inhibition of cell cycle progression in human fibrosarcoma HT1080 cells. Reported to be more potent than SAHA in inhibiting tumor growth in a murine xenograph model in vivo.
1.Kim, D.H., et al. 2007. Biochem. Biophys. Res. Commun. 356, 233.
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