IWP L6

$120.00$500.00

Product Specification

  • Appearance
    :

    Off-white solid.

  • CAS Number
    :

    1427782-89-5

  • Cat.number
    :

    VD-OEIA-0142

  • Formula
    :

    C25H20N4O2S2

  • MW
    :

    472.58

  • Purity
    :

    >=98%.

  • Solubility
    :

    100 mM in DMSO.

  • Storage
    :

    +2°C to +8°C. Protect from light.

  • Synonyms
    :

    N/A

  • Size
    :

    10mg, 50mg

Product Variations

Product # Price Quantity  
VD-OEIA-0142-0010-10mg $120
VD-OEIA-0142-0050-50mg $500

Description

Potent inhibitor of Porcupine (Porcn), a membrane-bound O-acyltransferase (MBOAT) (EC50 = 0.5 nM). Shown to inhibit Wnt-dependent processes such as tailfin regeneration and posterior axis formation in zebrafish; also reduces branching morphogenesis in cultured mouse embryonic kidneys.
1.Wang et al (2013);  J.Med.Chem. 56 2700.

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