CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-0015-0010-10mg | $35 | ||
| VD-OEIA-0015-0050-50mg | $200 |
JNJ 10191584 maleate
$35.00 – $200.00
Product Specification
-
Appearance:
Off-white to light tan powder.
-
CAS Number:
869497-75-6
-
Cat.number:
VD-OEIA-0015
-
Formula:
C13H15ClN4O · C4H4O4
-
MW:
394.81
-
Purity:
≥97%
-
Solubility:
DMSO (≥10 mg/mL)
-
Storage:
RT
-
Synonyms:
VUF 6002 maleate
-
Size:
10mg, 50mg
Description
Highly selective histamine H4 receptor silent antagonist; binds with high affinity to the human H4 receptor (Ki = 26 nM) and is > 540-fold selective over the H3 receptor (Ki = 14.1 μM). In vitro, inhibits mast cell and eosinophil chemotaxis with IC50 values of 138 and 530 nM respectively. Orally active in vivo.
1.Terzioglu, N., et al. 2004. Bioorg. Med. Chem. Lett. 14: 5251-5256.
2.Venable, J.D., et al. 2005. J. Med. Chem. 48: 8289-8298.
3.Varga, C., et al. 2005. Eur. J. Pharmacol. 522: 130-138.
Reviews
There are no reviews yet.