CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-0040-0001-1mg | $120 | ||
| VD-OEIA-0040-0005-5mg | $280 |
JYL-1511 (CAS 623166-14-3)
$120.00 – $280.00
Product Specification
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Appearance:
Off-white solid.
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CAS Number:
623166-14-3
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Cat.number:
VD-OEIA-0040
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Formula:
C21H29N3O3S2
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MW:
435.6
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Purity:
>98% by NMR.
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Solubility:
Methanol, 100% Ethanol, DMSO or other organic solvents. Insoluble in water.
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Storage:
-20°C.
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Synonyms:
N-(4-tert-Butylbenzyl)-N’-[3-methoxy-4-(methylsulfonylamino)benzyl]thiourea
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Size:
1mg, 5mg
Description
JYL-1511 has been shown to act as a partial agonist for the transient receptor potential vanilloid-1 (TRPV1) channel. TRPV1 is a Capsaicin (sc-3577) receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH, and heat. Research indicates that the presence of Cyclosporin A increases the efficiency of JYL-1511.
1. Wang, Y., et al. 2003. Mol. Pharmacol. 64: 325-333.
2. Pearce, L.V., et al. 2008. Naunyn Schmiedebergs Arch. Pharmacol. 377: 149-157.
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