Lamivudine (CAS 134678-17-4)

$100.00$400.00

Product Specification

  • Appearance
    :

    White to off-white powder

  • CAS Number
    :

    134678-17-4

  • Cat.number
    :

    VD-HA-0262

  • Formula
    :

    C8H11N3O3S

  • MW
    :

    229.26

  • Purity
    :

    ≥98%

  • Solubility
    :

    DMSO: 20 mg/mL

  • Storage
    :

    RT

  • Synonyms
    :

    Epivir-HBV, Epivir, Heptovir, Zeffix

  • Size
    :

    500mg, 50mg

SKU: VD-HA-0262 Categories: ,

Product Variations

Product # Price Quantity  
VD-HA-0262-0010-50mg $100
VD-HA-0262-0500-500mg $400

Description

Lamivudine (CAS 134678-17-4) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It is an analogue of cytidine, and can inhibit both types (1 and 2) of HIV reverse transcriptase as well as the reverse transcriptase of hepatitis B. It needs to be phosphorylated to its triphosphate form before it is active. 3TC-triphosphate also inhibits cellular DNA polymerase.

1. James Fung et. al The American Journal of Gastroenterology, 108(6), 942-948 (2013)
2. Hans Damerow et. al Journal of Medical Virology, 82(11), 1850-1858 (2010)

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