MMP-9/MMP-13 Inhibitor I

$65.00$450.00

Product Specification

  • Appearance
    :

    White Solid

  • CAS Number
    :

    204140-01-2

  • Cat.number
    :

    VD-OEIA-00099

  • Formula
    :

    C25H25N3O6S

  • MW
    :

    495.6

  • Purity
    :

    ≥95%

  • Solubility
    :

    DMSO or MeOH

  • Storage
    :

    -20°C. Protect from light.

  • Synonyms
    :

    N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-(4- biphenylcarbonyl)piperazine-2-carboxamide

  • Size
    :

    10mg, 1mg

Product Variations

Product # Price Quantity  
VD-OEIA-00099-0001-1mg $65
VD-OEIA-00099-0010-10mg $450

Description

A piperazine-based, cell-permeable, and highly potent inhibitor of MMP-9 (IC50=900 pM) and MMP-13 (IC50=900 pM). Reported to inhibit MMP-1 and MMP-3 at much higher concentrations (IC50=43 nM and 23 nM, respectively). Also acts as an inhibitor of MMP-7 (IC50=930 nM).

1. Cheng, M., et al. 2000. J. Med. Chem. 43: 369-380.

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