Nutlin-3a chiral (CAS 675576-98-4)

$100.00$450.00

Product Specification

  • Appearance
    :

    White powder.

  • CAS Number
    :

    675576-98-4

  • Cat.number
    :

    VD-AIH-0290

  • Formula
    :

    C30H30Cl2N4O4

  • MW
    :

    581.49

  • Purity
    :

    >=98%.

  • Solubility
    :

    DMSO

  • Storage
    :

    -20°C

  • Synonyms
    :

    MDM2 Antagonist IV

  • Size
    :

    10mg, 50mg

SKU: VD-AIH-0290 Categories: ,

Product Variations

Product # Price Quantity  
VD-AIH-0290-0010-10mg $100
VD-AIH-0290-0050-50mg $450

Description

Nutlin-3a chiral is a cell-permeable and highly potent active enantiomer of Nutlin-3 that binds to the p53-binding pocket and blocks the interaction of p53 and MDM2.

1.Shen, H. and Maki, C.G., 2010. J. Biol. Chem. 285, 23105.
2.Thompson, T., et al. 2004. J. Biol. Chem. 279, 53015.

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