CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-AIH-0287-0005-5mg | $140 | ||
| VD-AIH-0287-0025-25mg | $550 |
OSI 906
$140.00 – $550.00
Product Specification
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Appearance:
Not available
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CAS Number:
867160-71-2
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Cat.number:
VD-AIH-0287
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Formula:
C26H23N5O
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MW:
421.19
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Purity:
>=98%
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Solubility:
DMSO
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Storage:
-20°C.Protect from light.
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Synonyms:
Linsitinib
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Size:
25mg, 5mg
Description
Linsitinib (OSI 906) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR-1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis.
1.Buck E, Mulvihill M, Iwata KK. Mt Sinai J Med. 2010 Jul-Aug;77(4):358-65.
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