Ro-20-1724

$200.00$750.00

Product Specification

  • Appearance
    :

    White solid.

  • CAS Number
    :

    29925-17-5

  • Cat.number
    :

    VD-OEIA-1013

  • Formula
    :

    C15H22N2O3

  • MW
    :

    278.4

  • Purity
    :

    >=99% by (TLC)

  • Solubility
    :

    DMSO or EtOH.

  • Storage
    :

    RT. Keep cool and dry.

  • Synonyms
    :

    4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone

  • Size
    :

    1g, 5g

Product Variations

Product # Price Quantity  
VD-OEIA-1013-0001-1g $200
VD-OEIA-1013-0005-5g $750

Description

A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50 = 2 µM). Inhibits superoxide generation and arachidonic-induced platelet aggregation. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells.

1.Sheppard, H., et al. 1972. Adv Cyclic Nucleotide Res. 1: 103-112.
2.Reeves, M.L., et al. 1987. Biochem. J. 241: 535-541.
3.Katano, Y., et al. 1990. Biochem. Biophys. Res. Commun. 167:123-129.

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