CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-AM-0054-0010-10mg | $70 | ||
| VD-AM-0054-0050-50mg | $300 |
SU 16f (CAS 251356-45-3)
$70.00 – $300.00
Product Specification
-
Appearance:
Red-brown solid
-
CAS Number:
251356-45-3
-
Cat.number:
VD-AM-0054
-
Formula:
C24H22N2O3
-
MW:
386.44
-
Purity:
≥98%
-
Solubility:
100 mM in DMSO
-
Storage:
RT
-
Synonyms:
5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol- 3-ylidene)methyl ]-2,4-dimethyl-1H-pyrrole-3-propanoic acid
-
Size:
10mg, 50mg
Description
SU 16f (CAS 251356-45-3) is a potent and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor (IC50 = 10 nM) that displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. Inhibits proliferation of HUVEC and NIH3T3 cells in vitro (IC50 = 0.11 μM).
1. Sun et al (1999) J.Med.Chem. 42 5120.
Reviews
There are no reviews yet.