CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-10018-0001-1mg | $30 | ||
| VD-OEIA-10018-0005-5mg | $100 |
Syk Inhibitor
$30.00 – $100.00
Product Specification
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Appearance:
Deep orange solid.
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CAS Number:
622387-85-3
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Cat.number:
VD-OEIA-10018
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Formula:
C18H15N3O3S
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MW:
353.4
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Purity:
≥97% (sum of two isomers)
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Solubility:
DMSO
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Storage:
+2°C to +8°C. Protect from light.
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Synonyms:
Spleen Tyrosine Kinase Inhibitor
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Size:
1mg, 5mg
Description
A cell-permeable oxindole compound that acts as a potent, reversible, and ATP-competitive Syk inhibitor (IC50=14 nM). Has been shown to effectively inhibit FcεRI-mediated degranulation in the rat basophilic leukemia cell line, RBL-2H3 (EC50=313 nM).
1.Lai, J.Y.Q., et al. 2003. Bioorg. Med. Chem. Lett. 13, 3111.
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