TAPI-0

$200.00$800.00

Product Specification

  • Appearance
    :

    White solid.

  • CAS Number
    :

    143457-40-3

  • Cat.number
    :

    VD-OEIA-1085

  • Formula
    :

    C24H32N4O5

  • MW
    :

    456.5

  • Purity
    :

    >=97%

  • Solubility
    :

    50% Acetic Acid or DMSO.

  • Storage
    :

    -20°C.Protect from light.

  • Synonyms
    :

    TNF-α Protease Inhibitor-0

  • Size
    :

    1mg, 5mg

Product Variations

Product # Price Quantity  
VD-OEIA-1085-0001-1mg $200
VD-OEIA-1085-0005-5mg $800

Description

A hydroxamate-based inhibitor of collagenase, gelatinase, and TACE (TNF-α converting enzyme/ADAM17; IC50 = 100 nM). Blocks spontaneous and PMA-induced release of TNF-α in transfected COS 7 cells.

1.Hooper, N.M., et al. 1997. Biochem. J. 321, 265.
2.Mullberg, J., et al. 1995. J. Immunol. 155, 5198.
3.Mohler, K.M., et al. 1994. Nature 370, 218.

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