Product Variations
Product # | Price | Quantity | |
---|---|---|---|
VD-OEIA-1004-0005-5mg | $100 | ||
VD-OEIA-1004-0025-25mg | $400 |
$100.00 – $400.00
Yellow solid
N/A
VD-OEIA-1004
C17H13N3O2 • CF3CO2H
405.3
>=98%
DMSO
+2°C to +8°C. Protect from light.
uPA Inhibitor II
25mg, 5mg
Product # | Price | Quantity | |
---|---|---|---|
VD-OEIA-1004-0005-5mg | $100 | ||
VD-OEIA-1004-0025-25mg | $400 |
A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activator (uPA; IC50=200 nM) with much reduced activity against trypsin, thrombin, tPA, and plasmin (38%, 8%, 5%, and 0% inhibition, respectively, with 100 µM UK122). Shown to effectively inhibit the migration and invasion (80% and 68% inhibition, respectively, with 100 µM UK122), but not proliferation, of uPA-expressing CFPAC-1 pancreatic cells.
1.Zhu, M., et al. 2007. Mol. Cancer Ther. 6, 1348.
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