CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-PI-0175-0010-10mg | $35 | ||
| VD-PI-0175-0100-25mg | $70 |
Z-Val-Phe-CHO (Calpain Inhibitor III)
$35.00 – $70.00
Product Specification
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Appearance:
White lyophilized solid
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CAS Number:
88191-84-8
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Cat.number:
VD-PI-0175
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Formula:
C22H26N2O4
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MW:
382.5
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Purity:
>=97%
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Solubility:
DMSO
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Storage:
+2°C to +8°C.
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Synonyms:
Carbobenzoxy-valinyl-phenylalaninal, MDL 28170
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Size:
10mg, 25mg
Description
A potent, cell-permeable inhibitor of calpain I and II (Ki = 8 nM). Reduces capsaicin-mediated cell death in cultured dorsal root ganglion. Reported to block A23187-induced suppression of neurite outgrowth in isolated hippocampal pyramidal neurons. Exhibits neuroprotective effect in glutamate-induced toxicity.
1. Song, D.K., et al. 1994. J. Neurosci. Res. 39: 474-481.
2. Chard, P.S., et al. 1995. Neuroscience. 65: 1099-1108.
3. Li, P.A., et al. 1998. Neurosci. Lett. 247: 17-20.
4. Ray, S.K., et al. 2000. Brain Res. 852: 326-334.
5. Jiang, Q., et al. 2000. J. Neurochem. 74: 2101-2107
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