CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-0013-0010-1mg | $90 | ||
| VD-OEIA-0013-0050-5mg | $350 |
ZM 336372
$90.00 – $350.00
Product Specification
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Appearance:
Off-white solid
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CAS Number:
208260-29-1
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Cat.number:
VD-OEIA-0013
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Formula:
C23H23N3O3
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MW:
389.4
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Purity:
≥95% by HPLC
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Solubility:
DMSO
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Storage:
-20°C. Protect from light.
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Synonyms:
N-[5-(3-Dimethylaminobenzamido)-2-methylphenyl]-4-hydroxybenzamide
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Size:
1mg, 5mg
Description
A potent and specific inhibitor of the protein kinase c-Raf (IC50 = 70 nM). Inhibits c-Raf with ten-fold increased potency compared to B-Raf, but does not inhibit many other protein kinases (even at 50 M) with the exception of SAPK2a/p38(IC50 = 2 M) and SAPK2b/p382 (IC50 =2 M). The inhibition of c-Raf by ZM 336372 is competitive with respect to ATP.
1.C.A. Hall-Jackson, et al.; Chem. Biol. 6, 559 (1999).
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