CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-1068-0010-10mg | $100 | ||
| VD-OEIA-1068-0050-50mg | $350 |
ALK5 Inhibitor II
$100.00 – $350.00
Product Specification
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Appearance:
Yellow solid.
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CAS Number:
446859-33-2
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Cat.number:
VD-OEIA-1068
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Formula:
C17H13N5
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MW:
287.32
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Purity:
>=97%
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Solubility:
100 mM in DMSO and to 50 mM in Ethanol.
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Storage:
+2°C to +8°C. Protect from light.
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Synonyms:
SJN 2511; RepSox
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Size:
10mg, 50mg
Description
Selective inhibitor of the TGF-β type I receptor ALK5 (IC50 values are 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding respectively). Selective for ALK5 over a range of kinases, including p38 MAPK, JNK1 and GSK3 (IC50 > 16 μM). Enhances the efficiency of cellular reprogramming.
1.Gellibert et al (2004). J.Med.Chem. 47 4494.
2.Li et al (2009). Cell Stem Cell 4 16.
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