CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-PI-0001-0005-5mg | $90 | ||
| VD-PI-0001-0025-25mg | $350 |
Aminopeptidase N Inhibitor
$90.00 – $350.00
Product Specification
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Appearance:
Off-white solid
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CAS Number:
Not available.
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Cat.number:
VD-PI-0001
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Formula:
C17H10N2O8
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MW:
370.3
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Purity:
≥98%
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Solubility:
DMSO
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Storage:
+2°C to +8°C. Protect from light.
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Synonyms:
APN/CD13 Inhibitor
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Size:
25mg, 5mg
Description
A dinitroflavone compound that acts as a selective, reversible, and competitive inhibitor of aminopeptidase N (APN/CD13; IC50=25 µM in U937 cells). Displays ~2-3 fold lower inhibition potency than Bestatin, but is not cytotoxic. Does not induce apoptosis, and only weakly affects the activities of MMP-9, angiotensin converting enzyme, neural endopeptidase, γ-glutamyl transpeptidase, DPPIV, and cathepsin-G even at concentrations as high as 1 mM.
1.Bauvois, B., et al. 2003. J. Med. Chem. 46, 3900.
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