AS 252424

$20.00$80.00

Product Specification

  • Appearance
    :

    Yellow to brown crystalline solid.

  • CAS Number
    :

    900515-16-4

  • Cat.number
    :

    VD-OEIA-1028

  • Formula
    :

    C14H8FNO4S

  • MW
    :

    305.3

  • Purity
    :

    >98 %

  • Solubility
    :

    DMSO or EtOH.

  • Storage
    :

    -20°C

  • Synonyms
    :

    (Z)-5-((5-(4-fluoro-2-hydroxyphenyl)furan- 2-yl)methylene)thiazolidine-2,4-dione

  • Size
    :

    1mg, 5mg

Product Variations

Product # Price Quantity  
VD-OEIA-1028-0001-1mg $20
VD-OEIA-1028-0005-5mg $80

Description

Potent and selective phosphoinositide 3-kinase PI3-kinase p110γ inhibitor shown to be selective for class IB PI3-kinase-mediated cellular effects.

1. Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils: A.M. Condliffe, et al.; Blood 106, 1432 (2005).
2. Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma: V. Pomel, et al.; J. Med. Chem. 49, 3857 (2006).

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