CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-AIH-0283-0005-10mg | $90 | ||
| VD-AIH-0283-0050-50mg | $400 |
Bax Channel Blocker
$90.00 – $400.00
Product Specification
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Appearance:
White Solid
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CAS Number:
Not available
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Cat.number:
VD-AIH-0283
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Formula:
C19H21Br2N3O·2CF3CO2H
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MW:
695.3
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Purity:
≥95%
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Solubility:
DMSO
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Storage:
+4°C.
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Synonyms:
1-(3,6-dibromo-9H-carbazol-9-yl)-3-(piperazin-1-yl)propan-2-ol
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Size:
10mg, 50mg
Description
A cell-permeable dibromocarbazolo-piperazinyl derivative that displays anti-apoptotic properties. Effectively blocks Bid-induced cyctochrome c release from HeLa cell mitochondria by inhibiting Bax channel-forming activity.
1.Peixoto, P., et al. 2009. Biochem J. 423, 381.
2.Bombrun, A., et al. 2003. J. Med. Chem. 46, 4365.
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