CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-AIH-0278-0010-10mg | $90 | ||
| VD-AIH-0278-0100-100mg | $850 |
CAY10578
$90.00 – $850.00
Product Specification
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Appearance:
Crystalline solid
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CAS Number:
19231-60-8
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Cat.number:
VD-AIH-0278
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Formula:
C10H3I4NO4
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MW:
708.8
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Purity:
>=95% by HPLC
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Synonyms:
2-(4,5,6,7-tetraiodo-1,3-dioxoisoindolin-2-yl)acetic acid
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Size:
100mg, 10mg
Description
CK2 is known to negatively regulate apoptosis, and increased activity has been noted in many proliferating tissues and tumors, which lends promise as an anticancer drug target. CAY10578 is a potent inhibitor of CK2 and is ATP competitive, only minimally inhibiting the activities of other protein kinases.
1. Golub, A.G., Yakovenko, O.Y., Prykhod’ko, A.O., et al. Evaluation of 4,5,6,7-tetrahalogeno-1H-isoindole-1,3(2H)-diones as inhibitors of human protein kinase CK2. Biochem Biophys Acta 1784 143-149 (2008).
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