CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-ACR-0003-0050-250mg | $100 | ||
| VD-ACR-0003-0001-1g | $300 |
Cisplatin (CAS 15663-27-1)
$100.00 – $300.00
Product Specification
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Appearance:
Yellow to orange powder or crystals.
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CAS Number:
15663-27-1
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Cat.number:
VD-ACR-0003
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Formula:
Cl2H6N2Pt
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MW:
300.05
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Purity:
>=99%
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Solubility:
50 mM in DMSO.
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Storage:
RT
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Synonyms:
CDDP, cis-Diaminodichloroplatinum
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Size:
1g, 250mg
Description
Cisplatin (CAS 15663-27-1) is a potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of apoptosis protein (XIAP) expression and activates caspase-3. In certain glioma cell lines, sensitizes cells to TNF-α-induced apoptosis.
1.Van Waardenburg, R.C., et al. 2004. J. Biol. Chem. 279: 54502-54509.
2. Seki et al (2000) Cancer Chemother.Pharmacol. 45 199.
3. Duan et al (2004) Clin.Cancer Res. 10 234.
4. Nomura et al (2004) Urol.Oncology 22 453.
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