CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-IS-0063-0010-10mg | $90 | ||
| VD-IS-0063-0050-50mg | $450 |
LFM-A13 (CAS 62004-35-7)
$90.00 – $450.00
Product Specification
-
Appearance:
Pale brown solid
-
CAS Number:
62004-35-7
-
Cat.number:
VD-IS-0063
-
Formula:
C11H8Br2N2O2
-
MW:
360
-
Purity:
≥97% by HPLC
-
Solubility:
DMSO
-
Storage:
+2°C to +8°C. Protect from light.
-
Synonyms:
LFMA13
-
Size:
10mg, 50mg
Description
LFM-A13 (CAS 62004-35-7) is a potent and selective inhibitor of Bruton’s tyrosine kinase (BTK). Inhibits recombinant BTK with an IC50 value of 2.5 μM and has no activity on other protein kinases ( including JAK1, JAK3, HCK, EGFR kinase and insulin receptor kinase) at concentrations of up to 278 μM.
1. Mahajan et al (1999) J.Biol.Chem. 274 9587.
2. Vassilev et al (1999) J.Biol.Chem. 274 1646.
3. Crosby and Poole (2002) J.Biol.Chem. 277 9958.
4. Uckun, F.M., et al. 2006. Bioorg. Med. Chem. In press.
5. Mahajan, S., et al. 1999. J. Biol. Chem. 274, 9587.
6.Vassilev, A., et al. 1999. J. Biol. Chem. 274, 1646.
Reviews
There are no reviews yet.