CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-AM-0105-0010-10mg | $60 | ||
| VD-AM-0105-0050-50mg | $255 |
Tranilast (CAS 53902-12-8)
$60.00 – $255.00
Product Specification
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Appearance:
Off-white solid
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CAS Number:
53902-12-8
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Cat.number:
VD-AM-0105
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Formula:
C18H17NO5
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MW:
327.34
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Purity:
≥98% (HPLC)
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Solubility:
100 mM in DMSO
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Storage:
2-8°C
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Synonyms:
2-[[3-(3,4-Dimethoxyphenyl)-1-oxo- 2-propenyl]amino]benzoic acid
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Size:
10mg, 50mg
Description
Tranilast (CAS 53902-12-8) is an anti-allergic via inhibition of chemical mediator release from mast cells. Most recently shown to be an effective inhibitor of angiogenesis. Demonstrated to antagonize the effects of angiotensin II on human arteries, possibly by an interaction at the level of the AT1 receptor.
1. Miyazawa et al (1996) Br.J.Pharmacol. 118 915.
2. Hishikawa et al (1996) J.Cardiovasc.Pharmacol. 28 200.
3. Isaji et al (1997) Br.J.Pharmacol. 122 1061.
4. Jin et al (1998) 361 199.
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