CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-ESA-0020-0100-100mg | $40 | ||
| VD-ESA-0020-0500-500mg | $140 |
Metformin hydrochloride (CAS 66575-29-9)
$40.00 – $140.00
Product Specification
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Appearance:
White Solid
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CAS Number:
1115-70-4
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Cat.number:
VD-ESA-0020
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Formula:
C4H11N5.HCl
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MW:
165.62
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Purity:
>95%
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Solubility:
100 mM in water and to 50 mM in DMSO
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Storage:
RT
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Synonyms:
Metformin hydrochloride
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Size:
100mg, 500mg
Description
Metformin hydrochloride (CAS 1115-70-4) is an antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines. Activates the aPKC-CBP pathway in neural precursors to promote neurogenesis.
1. Shaw et al (2005) Science 310 1642. 2. Towler and Hardie (2007) Circ.Res. 100 328.
3. Wang et al (2012) Cell Stem Cell 11 23.
4. Hirsch et al (2013) Proc.Natl.Acad.Sci.USA 110 972.
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