CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-CCR-0042-0010-10mg | $70 | ||
| VD-CCR-0042-0050-50mg | $300 |
NSC 146109 hydrochloride (CAS 59474-01-0)
$70.00 – $300.00
Product Specification
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Appearance:
Yellow solid.
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CAS Number:
59474-01-0
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Cat.number:
VD-CCR-0042
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Formula:
C17H16N2S.HCl
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MW:
316.85
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Purity:
≥99%
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Solubility:
10 mM in EtOH, 100 mM in DMSO
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Storage:
RT
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Synonyms:
(10-Methyl-9-anthracenyl)methyl carbamimidothioic acid ester hydrochloride
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Size:
10mg, 50mg
Description
NSC 146109 hydrochloride (CAS 59474-01-0) is a cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.
1. Dolma et al (2003) Cancer Cell 3 285.
2. Berkson et al (2005) Int.J.Cancer 115 701.
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