CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-AM-0103-1mg | $160 | ||
| VD-AM-0103-5mg | $650 |
Glycyl-H 1152 dihydrochloride (CAS 913844-45-8)
$160.00 – $650.00
Product Specification
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Appearance:
Not available
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CAS Number:
913844-45-8
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Cat.number:
VD-AM-0103
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Formula:
C18H24N4O3S.2HCl
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MW:
449.4
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Purity:
>98%
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Solubility:
DMSO or Water.
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Storage:
+2°C to +8°C.
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Synonyms:
(S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl)- sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride
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Size:
1mg, 5mg
Description
Glycyl-H 1152 dihydrochloride (CAS 913844-45-8) is a glycyl analog of the Rho-kinase inhibitor H 1152 dihydrochloride (VD-AM-0102) that displays improved ROCKII selectivity. IC50 values are 0.0118, 2.35, 2.57, 3.26, > 10 and >10 μM for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC respectively.
1. Tamura et al (2005) Development of specific Rho-kinase inhibitors and their clinical application. Biochim.Biophys.Acta 1754 245.
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