CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-AIH-0289-0010-10mg | $90 | ||
| VD-AIH-0289-0025-25mg | $180 |
Nutlin-3 (CAS 890090-75-2)
$90.00 – $180.00
Product Specification
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Appearance:
Solid
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CAS Number:
890090-75-2
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Cat.number:
VD-AIH-0289
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Formula:
C30H30Cl2N4O4
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MW:
581.5
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Purity:
>=95%.
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Solubility:
DMSO
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Storage:
-20°C
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Synonyms:
MDM2 Antagonist
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Size:
10mg, 25mg
Description
Nutlin-3, a tetra-substituted imidazoline, is a potent and selective small-molecule antagonist of murine double minute 2 (MDM2), which occupies the binding site of p53 in MDM2 and consequently prevent MDM2 binding to p53 leading to the disruption of the autoregulator feedback loop and the fostering of the p53 tumor suppressor network.
1.Circ Res. 2007; 100: 13-14.
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