CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-1064-0010-10mg | $150 | ||
| VD-OEIA-1064-0050-50mg | $500 |
PF 429242
$150.00 – $500.00
Product Specification
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Appearance:
White solid.
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CAS Number:
947303-87-9
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Cat.number:
VD-OEIA-1064
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Formula:
C25H35N3O2
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MW:
482.49
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Purity:
>=97%
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Solubility:
Water to 50 mM; DMSO to 100 mM; Ethanol to 100 mM.
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Storage:
+2°C to +8°C. Protect from light.
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Synonyms:
N/A
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Size:
10mg, 50mg
Description
Reversible, competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). Selective for site 1 protease against a panel of serine proteases. Inhibits rate of cholesterol synthesis in CHO cells (IC50 = 0.53 μM). Also displays antiviral activity. Cell permeable.
1.Hay et al (2007). Bioorg.Med.Chem.Lett. 17 4411.
2.Hawkins et al (2008). J.Pharmacol.Exp.Ther. 326 801.
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