Phorbol 12,13-dibutyrate (CAS 75567-37-2)

$90.00$250.00

Product Specification

  • Appearance
    :

    White lypophilised solid.

  • CAS Number
    :

    37558-16-0

  • Cat.number
    :

    VD-ESA-0024

  • Formula
    :

    C28H40O8

  • MW
    :

    504.61

  • Purity
    :

    >98%

  • Solubility
    :

    50 mM in DMSO

  • Storage
    :

    -20°C

  • Synonyms
    :

    Phorbol 12,13-dibutyrate

  • Size
    :

    10mg, 3mg

SKU: VD-ESA-0024 Category:

Product Variations

Product # Price Quantity  
VD-ESA-0024-0003-3mg $90
VD-ESA-0024-0010-10mg $250

Description

Phorbol 12,13-dibutyrate (CAS 37558-16-0) is a protein kinase C activator. Induces contraction of vascular smooth muscle and inhibits MLC phosphatase (MLCP) in vascular smooth muscle. Activity does not alter intracellular Ca2+ concentration. Also inhibits the activity of Na+,K+ ATPase in OK cells.

1. Middleton et al (1993) J.Biol.Chem. 268 15958.
2. Hori et al (1999)  J.Neurosci. 19 7262.
3. Sakai et al (2010) J.Smooth Muscle Res. 46 259.

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