CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-ESA-0028-0050-50mg | $70 | ||
| VD-ESA-0028-0250-250mg | $290 |
Ranolazine dihydrochloride (CAS 95635-56-6)
$70.00 – $290.00
Product Specification
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Appearance:
White Solid
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CAS Number:
95635-56-6
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Cat.number:
VD-ESA-0028
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Formula:
C24H33N3O4.2HCl
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MW:
500.4
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Purity:
>99%
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Solubility:
100 mM in water and to 100 mM in DMSO.
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Storage:
RT
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Synonyms:
Ranolazine dihydrochloride, RS 43285
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Size:
250mg, 50mg
Description
Ranolazine dihydrochloride (CAS 95635-56-6) is an antianginal agent with antiarrhythmic properties that acts as a partial fatty acid oxidation inhibitor. Activates pyruvate dehydrogenase in ischemic myocytes to promote glucose oxidation, switching substrate utilization from fatty acids to glucose. Also shown to inhibit late INa and IKr currents.
1. Zacharowski et al (2001) Eur.J.Pharmacol. 418 105.
2. Shryock and Belardinelli (2008) Br.J.Pharmacol. 153 1128.
3. Wang et al (2008) J.Pharmacol.Exp.Ther. 325 875.
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