Razoxane (CAS 21416-67-1)

$50.00$190.00

Product Specification

  • Appearance
    :

    Solid.

  • CAS Number
    :

    21416-67-1

  • Cat.number
    :

    VD-AM-0056

  • Formula
    :

    C11H16N4O4

  • MW
    :

    268.27

  • Purity
    :

    >=98%

  • Solubility
    :

    DMSO(40 mg/ml).

  • Storage
    :

    RT. Keep cool and dry.

  • Synonyms
    :

    4,4′-(propane-1,2-diyl)bis(piperazine-2,6-dione)

  • Size
    :

    25mg, 5mg

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Product Variations

Product # Price Quantity  
VD-AM-0056-0005-5mg $50
VD-AM-0056-0025-25mg $190

Description

Razoxane (CAS 21416-67-1) is clinically active against angiogenesis and metastasis. Razoxane specifically inhibits topoisomerase II without inducing DNA strand breaks (topo II catalytic inhibitor). It is an antimitotic agent with immunosuppressive properties. Razoxane inhibits blood-borne and lymphatic metastases in different experimental models. Studies have shown that razoxane inhibits specifically the vasculogenic mimicry of B16F10 melanoma cells.

1. Rhomberg W., et al. Clin. Exp. Metastasis 25, 75-80, (2008).

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